Internship and thesis proposals
Study of the photophysics of phototransformable fluorescent proteins for improved super-resolution microscopy

Domaines
Biophysics
Physics of living systems
Nanophysics, nanophotonics, 2D materials and van der Waals heterostructures,, surface physicss, new electronic states of matter

Type of internship
Expérimental
Description
We have recently demonstrated the significant benefits of event-based sensors in single-molecule localization microscopy (SMLM) super-resolution imaging. Surpassing the performance of traditional scientific cameras, these sensors expand the horizons of temporal resolution in SMLM. Event-based sensors, inspired by the human eye, are characterized by their asynchronous and independent pixels, which detect changes in brightness with high temporal precision. Thus, the EveSMLM technique (event-based SMLM) notably allows for capturing detailed profiles of intensity fluctuations and blinking of each observed molecule. This internship focuses on exploring the EveSMLM technique for studying the photophysics of photoconvertible fluorescent proteins.
Contact
Ignacio Izeddin
Laboratory : Institut Langevin - UMR7587
Team : Imagerie pour la biologie et la santé
Team Website
/ Thesis :    Funding :