Internship and thesis proposals
Collective fluid-structure interactions of bio-inspired active channels

Domaines
Soft matter
Physics of liquids
Physics of living systems
Hydrodynamics/Turbulence/Fluid mechanics

Type of internship
Théorique, numérique
Description
From unicellular organisms to humans, liquid flows in vascular networks are among the most effective ways to transport matter and information for life. In mammals, the lymphatic network provides interstitial fluid transport from tissues to the cardiovascular system in the absence of a central pumping system. Instead, robust fluid transport emerges from the coordination of local fluid-structure interactions, combining active vessel contractions and passive leaflet deformation (Fig. 1(a)). The asymmetric flow-structure behavior of the leaflets provides flow directionality and results in net flow transport in response to contractions. Understanding this natural design is essential for understanding dysfunctions of the lymphatic system and for inspiring the design of engineered systems capable of autonomous and robust fluid transport. How did nature select the optimal distance between leaflets? Without physiological constraints, can we design a system more efficient than nature to transport fluid? Can we control complex collective behavior of the leaflets, such as waves? To address these questions, we have designed a bio-inspired experimental setup in which a bed of soft leaflets responds to wall contractions in a mini-channel (Fig. 1(b)). The goal of the internship is to develop and apply a computational/theoretical framework that can help us understand the collective flow-structure response of the leaflets.

Contact
Simon Gsell
Laboratory : IRPHE - UMR7342
Team : milieu vivant systemes biologiques
Team Website
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