Domaines
Statistical physics
Biophysics
Soft matter
Physics of living systems
Type of internship
Théorique, numérique Description
Self-organization is key to the function of living cells -- but sometimes goes wrong! In Alzheimer's and many other diseases, normally soluble proteins thus clump up into pathological fiber-like aggregates. While biologists typically explain this on the grounds of detailed molecular interactions, we have started proving that such fibers are actually expected from very general physical principles. We thus show that geometrical frustration builds up when mismatched objects self-assemble, and leads to non-trivial aggregate morphologies, including fibers.
Contact
Martin Lenz
Laboratory : LPTMS - UMR 8626
Team : Disordered systems, soft matter, interface physics
Team Website
Team : Disordered systems, soft matter, interface physics
Team Website