Domaines
Condensed matter
Biophysics
Soft matter
Nonequilibrium statistical physics
Physics of living systems
Non-equilibrium Statistical Physics
Type of internship
Expérimental Description
This project aims to study the role of activity and anisotropy in the mechanics of cellular monolayers. Activity is found in systems which are out-of-equilibrium. They consume energy at the microscopic level, such as ATP hydrolysis in cells, which allows them to generate active stresses, such as contractile forces in the acto-myosin network in cells. Anisotropy is found in systems which have elongated particles, or cells, leading to different properties along the X or Y direction. Traditional mechanical characterization of biological tissues considers them as passive and isotropic materials. This project will close this gap using a novel in vitro system: the microstretcher.
Contact
Claire Dessalles